Cell Structure and Organisation (CC2): Eduqas A Level Biology Exam Questions by Topic

Cell structure is one of the five Core Concepts at the start of the Eduqas course. You need the structure and function of each organelle, how prokaryotic cells and viruses differ from eukaryotic cells, and how cells are organised into tissues, organs and organ systems. Questions marked AS are from the AS papers (B400); the rest are from the A level papers (A400), where this topic keeps coming back in other contexts, from sperm cells to gene technology.

Many of the marks are for naming organelles on electron micrographs and then saying what they do in the cell in the question. The examiners' reports repeat a few points: learn what organelles look like on real micrographs, say "one type of cell" when you define a tissue, and give the precise feature (70S ribosomes, a peptidoglycan cell wall) rather than a vague one.

I don't teach the Eduqas specification myself, so for one-to-one help I recommend Sam. He teaches Eduqas A level Biology at a top-rated sixth form college and is very popular with his students. You can ask about lessons with Sam on WhatsApp using the link at the bottom of this page.

What you need from GCSE and Year 12

Each question on this page assumes you're secure on these ideas. If any of them feels shaky, look it up before you start.

  • Animal and plant cells have a nucleus, cytoplasm and a cell surface membrane; plant cells also have a cell wall, chloroplasts and a permanent vacuole.
  • Bacterial cells have no nucleus; their DNA is a loop in the cytoplasm, and they may have plasmids.
  • Proteins are made on ribosomes using the code carried by mRNA.
  • An electron microscope has a much higher resolution than a light microscope.

Key terms

These words come up in the questions and mark schemes. Examiners expect you to use them exactly.

  • Organelle: a structure inside a cell with a particular function, such as a mitochondrion or the Golgi body.
  • Lysosome: a vesicle containing hydrolytic (digestive) enzymes that break down old organelles and other material.
  • Exocytosis: release of material from a cell when a vesicle fuses with the cell surface membrane.
  • 70S ribosome: the smaller ribosome found in prokaryotes, mitochondria and chloroplasts (eukaryotic cytoplasm has 80S).
  • Endosymbiotic theory: the idea that mitochondria and chloroplasts came from prokaryotes taken into an ancestral cell.
  • Capsid: the protein coat around the nucleic acid of a virus.
  • Tissue: a group of similar cells (one type) working together to perform a function.
  • Organ: a group of different tissues working together to perform a function.

What these questions cover (Eduqas CC2)

The questions test these statements from Core Concept 2 of the Eduqas A level Biology specification (A400). Core Concepts are taught in Year 12, examined in AS Component 1 and tested again in every A level paper.

  • (a) the structure and function of the following
  • (b) the structure of prokaryotic cells and viruses
  • (c) cell theory and the similarities and differences in the cell structures of eukaryotes (animal and plant), prokaryotes and viruses, including the examination of a range of
  • (d) the levels of organisation including aggregation of cells into tissues and tissues into organs and organs into organ systems and also the examination of a range of prepar

How to use this page

Write your answer on paper before you open the mark scheme. Allow about 1.2 minutes per mark: the 20 questions are worth 39 marks, so about 47 minutes in total. Then mark your answer strictly against the mark scheme and read the examiners' tip underneath it. If you'd rather print the questions, download the PDF pack.

Organelles on micrographs

Question 1

AS Component 1 · June 2024 · Q2(a)(i) · 1 mark · Easy

Identify two structures on an electron micrograph of a plant cell.

Exam question: (i) Identify the structures labelled A and B in Image 2.1.
Show the mark scheme Mark scheme: A = Chloroplast and B = Vacuole (1)

Tap an image to open it full size.

Question 2

AS Component 1 · June 2024 · Q2(a)(iii) · 1 mark · Easy

Explain why internal features of a chloroplast wouldn't show under a light microscope.

Exam question: Image 2.1 shows some internal features of structure A. Suggest why these would not be visible if the cell had been viewed with a light microscope.
Show the mark scheme Mark scheme: Resolution too low / Not high enough magnification (1)

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From the examiners' report: Say that the resolution (or magnification) of the light microscope is too low. "Too small to see" on its own didn't score, and the light isn't absorbed by chlorophyll.

Question 3

AS Component 1 · June 2023 · Q3(c) · 2 marks

Pick out the chloroplast, nucleus and vacuole on an electron micrograph.

Exam question: Image 3.4 is an electron micrograph of a plant cell showing some organelles. Image 3.4 G A F E C B D Using letters (A–G) from Image 3.4, identify the organelles in Table 3.5.
Show the mark scheme Mark scheme: G D A All correct = 2 marks 2 correct = 1 mark 0/1 correct = 0 marks

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From the examiners' report: Some students couldn't identify the nucleus or the vacuole. Practise naming organelles on real, unlabelled electron micrographs.

Question 4

A level Component 2 · June 2018 · Q1(a) · 3 marks · Easy

Name the organelle that makes lysosomes, label a lysosome and give its function.

Exam question: The electron micrograph above shows the cell organelle responsible for producing lysosomes. Name the organelle, draw an arrow labelled L on the micrograph to identify a lysosome and describe a general function of lysosomes in normal cells.
Show the mark scheme Mark scheme: Correctly labelled lysosome (1) Golgi (apparatus/body) (1) Contain {hydrolytic/digestive} enzymes/{Break down/recycle} {organelles/macromolecules/debris}(1) Accept {transport/release} of enzymes within cell Reject disposal of waste unqualified/secrete enzymes

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From the examiners' report: The organelle is the Golgi body, not the endoplasmic reticulum. Many students described secretory vesicles instead of lysosomes: lysosomes contain hydrolytic enzymes that break down old organelles.

Organelles and their functions

Question 5

AS Component 1 · June 2018 · Q3(a)(i) · 1 mark

Use the percentages of each type of RNA to name the organelle with the most RNA.

Exam question: Name the organelle that would contain the greatest percentage of RNA. Explain your answer.
Show the mark scheme Mark scheme: ribosome + rRNA is ribosomal RNA/constituent of ribosomes (1) OR Nucleolus + synthesis of RNA

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From the examiners' report: Most students named the ribosome, but the explanation needs to say rRNA is part of the ribosome's structure, not that ribosomes are where translation happens.

Question 6

AS Component 1 · June 2022 · Q3(a) · 5 marks

Describe the sequence of events in making and secreting an enzyme.

Exam question: Describe the sequence of events involved in the production and secretion of enzymes as shown in Image 3.1.
Show the mark scheme Mark scheme: Any five (×1) from: A. mRNA (produced by transcription) leaves nucleus through nuclear pores B. Protein synthesis on ribosomes / protein in cisternae of rough ER (1) C. Vesicles containing protein pinch off rough ER and fuse with Golgi body / Vesicles from rough ER fuse to form Golgi apparatus (1) D. Protein is modifie

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From the examiners' report: Many students scored all five marks by following the route in order: mRNA leaves through a nuclear pore, protein is made on the rough ER, vesicles carry it to the Golgi body, it is modified, and a vesicle fuses with the membrane.

Question 7

AS Component 1 · June 2022 · Q3(b)(ii) · 3 marks · Easy

Name an organelle from an unusual micrograph and suggest its role in secretion.

Information from earlier in this question:

Earlier part of the same exam question, giving the information this part uses. Exam question: Name the organelle shown in Image 3.2 and suggest its function in enzyme secretion.
Show the mark scheme Mark scheme: Mitochondria (1) Produces ATP (1) ATP is a source of energy for exocytosis (1)

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From the examiners' report: Most students recognised mitochondria even though they looked unusual, because they had seen a wide range of images. Link ATP to exocytosis for the last mark.

Question 8

AS Component 1 · Autumn 2020 · Q2(b)(iii) · 2 marks

Suggest why enzyme-secreting cells have many mitochondria.

Exam question: Suggest why enzyme-secreting cells are observed to contain large numbers of mitochondria.
Show the mark scheme Mark scheme: To produce large amounts of ATP (1) For protein synthesis / exocytosis (1)

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From the examiners' report: Well answered: lots of ATP is needed, for protein synthesis and for exocytosis.

Question 9

A level Component 2 · June 2023 · Q5(b)(ii) · 1 mark

Explain why a cell contains more DNA than the length of its chromosomes.

Information from earlier in this question:

Earlier part of the same exam question, giving the information this part uses. Exam question: When the total length of DNA from a human male cell with DMD is calculated it is longer than 2.95 × 106 kilobases. Explain why.
Show the mark scheme Mark scheme: also DNA in the mitochondria Question 5 Total

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From the examiners' report: Name the mitochondria. "DNA outside the nucleus" wasn't enough.

Question 10

A level Component 2 · June 2025 · Q2(a) · 4 marks · Hard

Make a scientific drawing of a granum from a micrograph and label it.

Exam question: In the box below, produce a scientific drawing of the granum shown in Image 2.1. Label the stroma and thylakoid membrane on your diagram.
Show the mark scheme Mark scheme: 2 marks for a drawing that resembles the photo - has six plates and nothing extra 1 mark for a granum drawing /drawing with shading 0 marks if additional structures drawn Ignore ribosomes 1 mark for stroma correctly labelled 1 mark for thylakoid membrane correctly labelled

Tap an image to open it full size.

From the examiners' report: Draw only what is in the image: six plates and nothing extra. Many students drew a whole chloroplast and scored nothing, and the stroma is outside the granum, not inside.

Prokaryotes and viruses

Question 11

A level Component 1 · June 2024 · Q1(b)(i) · 2 marks

Give two features of mitochondria and chloroplasts that are also found in prokaryotes.

Exam question: Identify two structural features of mitochondria and chloroplasts that are also found in prokaryotic cells.
Show the mark scheme Mark scheme: Any two (×1) from: • 70S / smaller ribosomes (1) K • DNA circular / loop of DNA (1) • Ignore plasmids DNA free in stroma / matrix (1)

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From the examiners' report: Many students couldn't compare bacteria, mitochondria and chloroplasts. Learn the two shared features: 70S ribosomes and a circular loop of DNA.

Question 12

AS Component 1 · June 2018 · Q5(c)(iv) · 2 marks · Hard

Use a graph of organelle DNA to support the idea that organelles came from prokaryotes.

Information from earlier in this question:

Earlier part of the same exam question, giving the information this part uses. Exam question: Both mitochondria and chloroplasts are believed to have evolved from prokaryotes. What evidence does the graph provide that could support this hypothesis? Explain your answer.
Show the mark scheme Mark scheme: Any two (x1)from: single peak/spike for DNA from both organelles (1) Therefore there is only one molecule of DNA present (1) could be arranged as plasmids/circular DNA as found in bacteria (1)

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From the examiners' report: Most students couldn't interpret the graph. A single peak means one type of DNA molecule, which could be circular, like bacterial DNA.

Question 13

A level Component 2 · June 2023 · Q1(b)(ii) · 1 mark

Suggest why cyanobacteria were moved from the protoctists to the bacteria.

Exam question: Scientists used to classify cyanobacteria in the Kingdom Protoctista. With reference to their cell structure, suggest why they have been reclassified as bacteria.
Show the mark scheme Mark scheme: No {nucleus/ mitochondria/ golgi/ e.r/ chloroplasts}/ {smaller /70s} ribosomes/ murein cell wall/ peptidoglycan cell wall/ have plasmids Reject no membrane bound organelles

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From the examiners' report: No nucleus or 70S ribosomes both scored. A cell wall only counts if you say murein or peptidoglycan, because protoctists can have cellulose walls.

Question 14

AS Component 1 · June 2017 · Q2(b)(i) · 2 marks

Describe the structure of a virus and explain why it isn't a cell.

Exam question: Describe the structure of a virus and explain why it is not considered to be a cell.
Show the mark scheme Mark scheme: molecule of {nucleic acid / DNA / RNA} surrounded by a {protein coat / capsid} (1) (acellular as) {does not have membranes/ no organelles/ cell membranes/ cytoplasm} (1) Accept labelled diagram

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From the examiners' report: Don't confuse viruses with prokaryotic cells: a virus is nucleic acid in a protein coat, with no membranes, cytoplasm or organelles.

Comparing cells

Question 15

A level Component 1 · June 2018 · Q2(a)(i) · 1 mark

Give two features that distinguish a eukaryote from a prokaryote.

Exam question: (i) Describe two major features of a eukaryote which would allow you to distinguish it from a prokaryote.
Show the mark scheme Mark scheme: Any two for 1 mark from Have nucleus (1) membrane-bound organelles/ named example(1) 80S ribosomes (1) DNA associated in chromosomes/linear (1)

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From the examiners' report: Many students said eukaryotes don't have cell walls, which is wrong (plants and fungi do). Use a nucleus, membrane-bound organelles, 80S ribosomes or linear DNA.

Question 16

A level Component 2 · June 2024 · Q2(e) · 1 mark

Explain why cellulase isn't needed when extracting DNA from human cells.

Exam question: When DNA is extracted from plant cells the enzyme cellulase may need to be added. Explain why cellulase is not needed when extracting DNA from human cells. 
Show the mark scheme Mark scheme: Human cells do not have cell wall (1)

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From the examiners' report: Human cells have no cell wall at all. Saying the human cell wall isn't made of cellulose didn't score.

Question 17

AS Component 1 · June 2022 · Q3(b)(iii) · 3 marks · Easy

Suggest how a mitochondrion is able to replicate itself.

Information from earlier in this question:

Earlier part of the same exam question, giving the information this part uses. Exam question: The organelle shown in Image 3.2 is in the process of self-replication. This is a similar process to that seen in bacteria. Suggest and explain how this organelle is able to self-replicate.
Show the mark scheme Mark scheme: Mitochondria contain their own DNA / ref to endosymbiont theory (1) Mitochondria have ribosomes and can synthesise their own proteins (1) DNA can be replicated (so both new organelles have copy of DNA) / accept ref. to binary fission (1)

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From the examiners' report: This was well answered: mitochondria have their own DNA and ribosomes, so they can copy their DNA and make their own proteins.

Levels of organisation

Question 18

AS Component 1 · June 2024 · Q2(b)(i) · 1 mark · Easy

State the difference between a tissue and an organ.

Exam question: State the difference between a tissue and an organ.
Show the mark scheme Mark scheme: Tissue – one type of cell and Organ – many types of cell / many tissues / more than one tissue (1) Accept a tissue is a group of similar cells working together to perform a function whereas an organ is a group of tissues working together to perform a function

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From the examiners' report: A tissue is one type of cell. A common mistake was calling a tissue a collection of different cells.

Question 19

AS Component 1 · June 2018 · Q4(a)(ii) · 2 marks

Label a xylem vessel and explain why xylem vessels form a tissue.

Information from earlier in this question:

Earlier part of the same exam question, giving the information this part uses. Exam question: Label a xylem vessel on the photomicrograph above and explain why a group of xylem vessels form a tissue rather than an organ.
Show the mark scheme Mark scheme: correct label of a xylem vessel (1) only one type of cell/similar cells aggregated to perform the same function/OWTTE (1)

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From the examiners' report: More than half of students labelled a sieve tube element as xylem. The explanation needs similar cells working together to perform one function; vague answers didn't score.

Question 20

A level Component 3 · Autumn 2020 · Q1(b)(i) · 1 mark

Explain why blood is considered to be a tissue.

Exam question: Explain why blood is considered to be a tissue.
Show the mark scheme Mark scheme: A group of (similar) cells working together to perform a function

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From the examiners' report: This was the best answered part of the paper: a group of similar cells working together to perform a function.

Where students lose marks (from Eduqas examiners' reports and mark schemes)

Each point below is followed by wording that gained marks.

  • Golgi makes lysosomes: Some students named the endoplasmic reticulum and described secretory vesicles rather than lysosomes.

    ✔ Gains credit: "Golgi apparatus" and lysosomes "contain hydrolytic enzymes".

  • Resolution, not just size: Answers said the structures were too small to see without mentioning the microscope.

    ✔ Gains credit: "Resolution too low" or "not high enough magnification".

  • Draw what you see: Many students drew a whole chloroplast and placed the stroma inside the granum.

    ✔ Gains credit: A drawing with "six plates and nothing extra", with the stroma labelled outside the granum.

  • Qualify the cell wall: "Has a cell wall" didn't separate bacteria from protoctists.

    ✔ Gains credit: "Murein cell wall" or "peptidoglycan cell wall".

  • Viruses aren't prokaryotes: Some students mixed up viruses and prokaryotic cells.

    ✔ Gains credit: "Nucleic acid surrounded by a protein coat" with "no membranes or organelles".

  • No wall at all: Students said the human cell wall isn't made of cellulose.

    ✔ Gains credit: "Human cells do not have a cell wall".

  • A tissue is one cell type: A common error was calling a tissue a collection of different cells.

    ✔ Gains credit: "Tissue: one type of cell; organ: more than one tissue".

Download the questions

Download the PDF pack (20 questions, mark schemes at the end)

Keep practising

Questions, mark schemes and examiners' report extracts © WJEC CBAC Ltd (Eduqas).

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